Competitive Strategies for Wal-Mart

The emergence of Wal-Mart as a big box retailer has changed retail in the United States, according to a 2008 article on Wal-Mart and competition in AllBusiness. com. Big box retailers typically have stores exceeding 50,000 square feet. This type of store is standard, with large windowless single-story buildings. Several other big box retailers like Toys â€Å"R† Us, Best Buy, Target, Lowe's and Home Depot have created competition for Wal-Mart. However, Wal-Mart has stood out as the perennial merchandise big box retailer, according to the AllBusiness. om article. Because of its big box status, Wal-Mart has exceeded small retailers in profits. Annual revenues for 2004 were slightly over $288 billion. Revenues in 2006 exceeded $350 billion. Wal-Mart maintains its status as a big box retailer by seeking profits through a high volume of low-price items. Low-Cost Leadership Wal-Mart's slogan is â€Å"Spend Less. Live Better. † The giant retailer prides itself on providing customers with low-cost items that beat competitors. Wal-Mart reported a 3.6   percent increase in net income from cost cutting, according to an August 2010 Associated Press article. Also read MGMT-QUIZ about types of competitive strategies Customers are cautious about spending because of a slow economy, and Wal-Mart continues to be their low-cost option. Customers choose to shop at Super Wal-Mart centers for groceries, rather than the local grocery store because of discounted items. For example, Wal-Mart offers $1 ketchup bottles and $4 for a case of soda. The Associated Press article stated that Wal-Mart benefited during the recession as affluent shoppers were forced to downgrade to cheaper options.

Development Of Mathematical Understanding Education Essay

1.0 Introduction1.1 What is seminal fluid ; how it is made and what is it composed ofSeminal fluid is a substance found in many male species sexual generative secretory organs. Semen is the nebulose white organic structure fluid that is emitted from the urethra of the phallus during interjection. It is made up of a assortment of molecules and cells such as leukocytes, proteolytic and other enzymes every bit good as fruit sugar and is a medium for elimination and transit of sperm cell. In the human male species, production occurs in the prostate secretory organs and gonadal which are slightly thankless sex accoutrement secretory organs until they malfunction or cease to work at all with the prevailing effects being drastically lower the rates of birthrate. Semen is composed largely of H2O, likely about 90 % by weight. After that, it ‘s a mixture of amino acids ( proteins ) , minerals, saccharides ( sugars ) , and a little figure of other things. Semen has a basic pH degree intending it is the antonym of acidic by nature – this is to antagonize and neutralize the vagina ‘s acidic pH and increase the sperm cell ‘s opportunities of endurance. Beginning: ( hypertext transfer protocol: //www.orgasmpower.net/semen-production.html ) Besides sperm, seeds is made of secernments from the seven lower urinary piece of land constructions. These constructions include: seminal cysts ( which account for 60-70 % of the fluid ) , prostatic secretory organ ( which accounts for 20-30 % ) and the staying per centum is shared by the epididymis, vessel deferens, ampullae of the vessel, Cowper ‘s secretory organs and secretory organs of Littre. Semen itself has high concentrations of K, Zn, citric acid, fructose, phosphorylcholine, spermine, free amino acids, prostaglandins and enzymes, which nourish and protect the sperm. Beginning: ( hypertext transfer protocol: //www.menstuff.org/issues/byissue/semen.html # funfacts )SourceA : hypertext transfer protocol: //www.proceptin.com/phc/sperm-cell.phpMain Production sitesASeminal fluid is largely produced in four topographic points ; in the seminal cysts, the male testicles, the prostate secretory organ and in the Cowper ‘s secretory organs. The Seminal Vesicles: This is where the milklike white protein based substance ( semenogelin I and II ) that seeds largely consists of is chiefly produced ( Ulvsback et al. 1992 ) .A These semenogelins interact with each other and coagulumate after interjection ( Aumuller and Riva 1992 ) . ( Spermatozoa wellness depends on this substance for foods which they will utilize to prolong them on their manner to fertilise the female ova.A This fluid is besides alkalic in nature and helps to neutralize the acidic conditions within the female generative system. The Male Testes: This is the organ where the production of sperm cells occurs. Spermatozoa cells are cultivated here until they mature. After that they are so stored in the Ampulla where they wait to be ejaculated out of the organic structure. They are besides protected by glycocalyx secernments from the testicle, motorial canals, epididymis and accessary secretory organs ( Schroeter et al. 1999 ) . The Prostate Gland: The prostate secretory organ besides produces an alkalic solution that acts as a protective barrier for the sperm cells against the sourness of the female sexual generative environment. The pH of the fluid is maintained above 7 by the action of prostate prostasomes ( et Al. 1999 ) . The fluid produced, is a protastic serine peptidase and helps the liquification of the semenogelins clot ( Peter et al. 1998 ) The prostate is besides an of import beginning of superoxide anion aggregators in worlds ( Gavella et al. 1996 ) A The Cowper ‘s Glands: These secretory organs produce a clear slippery liquid besides known as pre-cum which is excreted during arousal or sexual stimulation.A It is produced by the Cowper ‘s or bulbouretheral secretory organs and creates a medium for which sperm can be transported and swim in through the male generative piece of land and acts as a lubricator to cut down clash during sexual activity.Seminal fluid Composition and mapsSemens contains citric acid, free amino acids, fructose, enzymes, phosphorylcholine, prostaglandin, K, and Zn. The mean volume of seeds produced in a individual interjection varies from 2 to 5 milliliter. The seeds from a individual interjection may incorporate between 40 million and 600 million sperm, depending on the volume of the semen and the length of clip since the last interjection. Samples used for medical intents are obtained by holding the giver masturbate. If a sample can non be produced without sexual intercourse, non-reactive rub bers can be used to roll up the seeds. The procedure of secernment of seminal fluid in male mammals is finally under androgenic and estrogenic control, with a intensifying consequence happening between these two types of gonadal steroids ( Reaside et al. 1999 ) . Oxytocin secreted by the posterior hypophysis, lactogenic hormone secreted by the front tooth can besides command activity of sexual accoutrement secretory organs in mammals ( Gemmell and Sernia 1989 ; Kumar and Farooq 1994 ; Gonzalez et Al. 1994 ; Watson et Al. 1999 ) . There is a general consensus that the three major functional facets of seminal fluid are, its function in sperm competition, its map to help birthrate and in conclusion its function in the transmittal of venereal diseases. This is due to the composing of the seminal fluid being attributed to the secernment of many different tissues and that are under the control of a assortment of different constituents of the neuroendocrine system. The functionality of the seminal fluid constituents may be duplicated but in the procedure they will synergize and complement each other. As an illustration, increased immunosuppressive action of the seminal fluid on the female generative piece of land aimed at increasing sperm viability may besides ease the transmittal of sexually catching pathogens, therefore increasing the choice force per unit area on females to get the better of immunosuppression. ( Birkhead et al. 1993 ) . Seminal fluid is responsible for sperm capacitation for the ability to fertilise female ‘s egg cell. Besides some proteins secreted by male accessary secretory organs have been implicated in the procedure of sperm capacitation. ( Gillott 1996 ) . Structural proteins of the spermatophre that are secreted by sex accoutrement secretory organs, such as trehalase and sugars such as trehalose, may play a function in the activation of sperm within the female ‘s Bursa copulatrix ( Yaginuma et al. 1996 ) . The procedure of capacitation of sperm involves the acquisition of a coat of saccharides that from the glycocalyx ( Schroeter et al. 1999 ) . Most of those saccharides are attached to proteins organizing glycoprotein composites that are produced by accessary secretory organs and other tissues of the male generative system. Acquisition of a glycocalyx is indispensable in some taxa for the attainment of full capacitation of sperm and fertilizing ability. ( Schroeter et al.1999 ) . In work forces, accessary secretory organs secrete 5†²-necleotidase, an enzyme that hydrolyses nuleotides into phosphate and nucleosides, which may play a function in the alteration of sperm surface during capacitation ( Konrad et al. 1998 ) . Capacitation in human sperm is besides increased by tripeptide amides found in seminal plasma ( Khan et al. 1992 ) . Other endocrines and substances are besides found in seminal fluid such as, edothelin which facilitates transit of sperm and besides heighten sperm motions through the womb by myometrial contraction stimulation ( casey et Al. 1992 ) . The same is the instance with bradykinin which helps transporation by its smooth musculus loosen uping belongingss ( Charlse Worth et Al. 1999 ) .1.2 Which metals have been found in seminal fluid and why?The interaction between metals and biomeolecules are important and major in biological categorizations. The metals preponderantly determine many metabolic reactions and fewer of them cat as the aetiological agents in environmentally induced neurological upsets. Aluminum, Zinc, Mg, Ca and lead hints can be round in seminal fluid in edge ionic signifier. These metals are of course found in minor hints and have an array of effects and utilizations and are collected in different avenues. It has been suggested that heavy metals may hold inauspicious impacts on male generative wellness [ Benoff S, Jacob A, Hurley, 2000 ; Telisman.S et Al, 2000 ] even at comparatively low exposures [ ; Telisman.S et Al 2007 ] . The heavy metals may adversely impact the male generative system, either by bring oning hypothalamic-pituitary axis break or by direct seeds quality decrease during spermatogenesis [ Wyrobek AJ et Al 1997 ] . Several metals are suspected endocrinal disruptor compounds and/or generative poisons such as chiefly lead ( Pb ) and Cd ( Cd ) . Human populations could be exposed to heavy metals at hint concentrations normally through consumption of contaminated H2O and nutrient or contact with contaminated air or dirt. Blood and seminal Pb concentrations every bit good as seeds quality among both occupationally exposed and unexposed work forces has been studied and concluded to hold a important opposite association [ De Rosa M et Al 2003 ; JurasoviA†¡ J et Al 2004 ; Telisman.S et Al, 2000, Eibensteiner L et Al 2005 ] . Cadmium has been connected to impaired seeds quality and altered hormonal degrees in work forces [ Pant N et Al 2003, Telisman.S et Al, 2000, Akinloye O et Al 2006 ; Zeng X et Al 2002 ] . Although Cd has been considered as an hormone disruptor, the mechanisms involved are non yet clear [ Henson MC et Al 2004 ] . Mercury ( Hg ) has been found to bring on abnormalcies in sperm morphology and motility in animate being vito surveies [ Mohamed MK et Al, 1987 ; Rao Mv et Al, 1989 ] . Choy et Al. [ Choy CM et Al, 2002 ] described Hg concentrations in seminal fluid and sperm abnormalcies in subfertile males. But contrary to that, Meeker et Al. [ Meeker JD et Al 2008 ] discounted that cl aim after happening no relationship between seeds quality and Hg degrees in blood. hypertext transfer protocol: //www.ehjournal.net/content/10/1/6ZincThe intent of seminal plasma Zn on sperm maps has been a subject of involvement to many scientists. Zinc organs from the prostate is good established and found in seminal plasma as Zn citrate or edge to glycoprotein derived from seminal cysts ( Marmar et al. 1975, Arver 1982, Arver and Eliasson 1982 ; Kavanagh 1983 ; Lafond et Al. 1986 ) has been recognised since 1921 ( Bertrand and Vladesco, 1921 ) It has been found that Zn is indispensable to the decondensation of chromatin at the right clip every bit good as stableness. ( kvist et Al. 1987,1988 ) . Zinc is thought to play a function as a refinisher of an built-in mechanism for head-tail withdrawal of sperm cell ( Bjorndahl and Kvist, 1982 ) . The entire benefit or injury of Zn is vague because it has been reported that high degrees of Zn concentrations have been related to lowered sperm mortality, whilst others have reported that high Zn content in seminal plasma to be associated with a high grade of sperm cell motility ( Stankovic and Mikac-Devic, 1976 ; Caldamone et Al. 1979 ) . Zinc lack is associated with hypogonadism and deficient development of secondary sex features in worlds ( Prasad, 1991 ) . Besides high Zn concentrations have been reported to deject oxygen consumption in the sperm cell ( Huacuja et al. , 1973 ; Foresta et al. , 1990 ) , and albumin-induced acrosome reaction ( Foresta et al. , 1990 ) . Zinc has besides been found to be responsible for the antibacterial activity of seminal plasma ( Fair et al. 1976 ) and decreases in degrees are seen in prostate infections ( Marmar et al. 1975, Abyholm et Al. 1981 ; Papadimas et Al. 1983 ) . The entire Zn content in seeds from mammals was found to be at high degrees, and Zn has been found to be critical to spermatogenesis. But Zn can besides do wasting of the seminiferous tubules in the rat and ensuing in the failure in spermatogenesis ( Millar et al. , 1958 ; Underwood, 1977 ; Endre et al. , 1990 ) . Besides, high concentrations of Zinc have been reported to deject oxygen consumption in the sperm cell ( Huacuja et al. , 1973 ; Foresta et al. , 1990 ) , and albumin-induced acrosome reaction ( Foresta et al. , 1990 ) . Consiquently there have been conflicting studies on the consequence of seminal Zn on sperm motility ( Stankovic and Mikac-Devic, 1976 ; Danscher et al. , 1978 ; Caldamone et al. , 1979 ; Lewis-Jones et al. , 1996 ) . One such struggle arises when it is demonstrated that chelation of Zn ions affects sperm motility ( Saito et al. , 1967 ; Danscher and Rebbe, 1974 ) , and it has been suggested that bioavailable Zn edge to vesicular high molecular weight proteins instead than entire seminal Zn should be a step of the consequence of Zn on sperm map ( Bjorndahl et al. , 1991 ; Carpino et al. , 1998 ) . hypertext transfer protocol: //molehr.oxfordjournals.org/content/5/4/331.full.pdf+html Like zinc Mg besides originates chiefly from the prostate secretory organ and the degrees of this component in seminal plasma reflect prostate map ( Eliasson and Lindhomer, 1972 ) . The Mg degrees normally closely correlative with those of zinc concentrations ( Adamopoulos and Deliyiannis, 1983 ) .Lead a metal best known for being environmentally harmful doing it teratogenic and abortifacient. Lead disposal in animate beings causes sterility. Lead is non of course present in high sums in the organic structure but can be increased due to industrial exposure. The lead exposure has been observed to do teratospermia and to expose positive correlativity to blood lead degrees ( Lancranjan et al.1975 ) . Seminal fluid is rich in Ca and helps modulate sperm map as the concentration of Ca in seeds determines sperm motility, the ability of sperm to travel. However surveies show that an increased concentration of Ca ion was damaging to human sperm motility.Calcium is of import for sperm physiology including motility ( Morton et al. , 1974 ; Lindemann et al. , 1987 ) , metamorphosis ( Peterson and Freund, 1976 ) , acrosome reaction, and fertilisation ( Yanagimachi and Usui, 1974 ; Yanagimachi, 1981 ) . The function of seminal Ca in sperm motility is, nevertheless, non to the full understood. Thomas and Meizel ( 1988 ) found chelation of extracellular Ca ions with EGTA to suppress acrosome reaction, but at the same clip to hold no consequence on motility.Metals are omnipresent at low degree concentrations and are ingested by the general population either voluntarily through addendums or involuntarily through consumption of contaminated nutrient and H2O or contact with contaminated dirt, du st, or air. Some metals, such as Cd, lead, arsenic, and quicksilver, are incidental xenobiotics that can be measured in most of the general popu- lation [ Centers for Disease Control and Prevention ( CDC ) 2005 ] . Because widespread human exposure and organic structure load have been demonstrated, there is turning concern for inauspicious wellness effects associated with low-level exposures encountered in the environment. Human and carnal grounds suggests that these metals may hold inauspicious impacts on male generative wellness at comparatively low lev- ELs. For illustration, Cd has been linked to hapless human seeds quality and DNA harm ( Telisman et al. 2000 ; Xu et Al. 2003 ) ; Pb may adversely impact sperm form, motility, and DNA unity ( Eibensteiner et al. 2005 ; Hernandez-Ochoa et Al. 2005 ; Jurasovic et Al. 2004 ; Telisman et al. 2007 ) ; and methyl- quicksilver is associated with sperm abnormalcies in subfertile males ( Choy et al. 2002 ) . However, human informations on nonoccupation al Exposure to these metals has been limited ( e.g. , Hg ) , missing ( e.g. , As ) , or inconsistent across surveies ( e.g. , Cd ) . We designed the present survey to research relationships between these incidental metals and seeds quality among work forces with exposure degrees that are likely to be representative of those found among the U.S. general population. Several other metals, such as Cr, Cu, manganese, Mo, Se, and Zn, are indispensable for good wellness but may be harmful above certain degrees [ Agency for Toxic Substances and Disease Registry ( ATSDR ) 2003, 2004, 2005 ; Greger 1999 ; Institute of Medicine ( IOM ) 2001 ] . For exam- ple, Cr, Mn, and Cu, which act as cofactors for a assortment of of import enzymes, have been associated with decreased seeds quality in gnawers and in worlds ( Adejuwon et al. 1996 ; Huang et Al. 2000 ; Kumar et Al. 2005 ; Telisman et al. 2000 ; Wirth et Al. 2007 ) . Mo is besides an of import cofactor for a limited num- ber of human enzymes and has demonstrated generative toxicity in carnal surveies ( IOM 2001 ) . On the other manus, low doses of metals such as Cu, Se, and Zn may hold protective effects on male generative results ( Benofft al. 1997 ; Evenson et Al. 1993 ; Lyubimov et Al. 2004 ; Olson et Al. 2005 ) and may help in antagonizing the effects of Cd, Pb, or other metals ( Telisman et al. 2000 ; Xu et Al. 2003 ) . Because the possible exists for a figure of metals to positively or negatively affect male reproduction either separately or together, we besides included these metals in our analysis. This wk represents the most comprehensive survey to day of the month on metal exposures at environ- mental degrees and human seeds quality.hypertext transfer protocol: //www.scribd.com/doc/7905524/Cadmium-Lead-and-Other-Metals-in-Relation-to-Semen-Quality-Human-Evidence-for-Molybdenum-as-a-Male-Reproductive-ToxicantTable 1.1 demoing the effects of different metals on male generative systemThe tabular array below shows what Marthur and her co-workers found on how different metals affect the human male and male animate beings ‘ generative systems. Table taken from Journal of Biological Science by Marthur et al. , 2010 The human race is going more and more industrialised and at the same time urbanised. This is one of many factors which has induced the effects of ionic edge metals in male generative systems and caused worldwide qui vive ( Chowdhury, 2009 ; Turgut et Al. 2003 ) . Marthur et al. , 2010 were looking at one of the most toxic and inauspicious effects with in the human males generative system. An inflow in natural stuffs ingestion rates and graduated table has made the presence of metal compounds in the environment of all time more omnipresent. Anthropogenetic activities have been established as one of the prima causes for ecotoxicological effects. Metallic elements are various in composing and toxic stoping points, so they can non portion an exact chemical footing in toxicology. Metallic elements in ionic signifier have a inclination to be sensitive and extremely reactive which means that they can respond with biological elements, such as the human male generative system in a figure of different ways. This in consequence allows exogenic metals to exercise toxic effects that are straight linked to steric re-arrangement which has been found to be responsible for biomolecule mal map. ( Kasprzak, 2002 and Kasprzak et al. , 2003 ) . After consumption, metals can easy flux to the male generative system where the procedure of spermatogenesis is left vulnerable to changes. Similarly, the metals can interact and respond with familial make-up of the human male endocrines. Low sperm mortality and has been established to be a direct consequence of exposure to metals. Looking back at this reappraisal it can be easy deduced that the toxicity and sensitiveness of metals can be mostly attributed to the hormonal change and spermatogenesis break and or malfunction. ( hypertext transfer protocol: //scialert.net/fulltext/ ? doi=jbs.2010.396.404 & A ; org=11 )1.3 A brief debut to aluminiumAluminum can be found bounteously in our environment. It is the 3rd most abundant component in the Earth ‘s crust, stand foring 8 % by weight of the entire constituents ( Martin, 1997 ) . The worlds are necessarily and invariably exposed to aluminium. High contents of aluminum can be found in some stones after the lithospheric rhythm where it is introduced into the Earth ‘s crust. Weathering of these stones is what causes aluminium-rich minerals to fade out, which forms indissoluble clay-like stuffs that finally are re-introduced into the Earth ‘s crust by deposit. Aluminium returns into the magma by farther subduction, which in bend completes the rhythm ( Exley, 2003 ) The attendant clay like stuffs play a important function in the lithospheric rhythm of aluminum so efficient ( Exely, 2003 ) these along with the hydroxyaluminosilicates, startle the aluminum content so that it does non over concentrate the biotic rhythm. Normally aluminium enters the encephalon through the blood-brain barrier ( BBB ) . It is suspected that the aluminum enters the encephalon by receptor-mediated endocytosis as a compound with beta globulin ( Roskams and Connor, 1990 ) . it has been reported that aluminum can come in into the encephalon as a compound with beta globulin which is bound to citrate through a specific transporter, Xca?’ ( l-glutamate/l-cysteine ) system money changer is the most likely agent as explained by Nagaswa. ( Nagasawa et al 2005 ) . High aluminum consumption has been related to the appearence a neurodegenerative disease ( Perl & A ; Moalem, 2006 ; Kawahara, 2005 ) . Aluminium has no biological benefit ( Yokel 2002 ) . It is a poison associated with some medical conditions such dialysis brain disorder ( Alfrey etA al. , 1976 ) , osteomalacia ( Parkinson etA al. , 1979 ) , and it has been found to hold links with many other diseases including Alzheimer ‘s disease ( Exley 1999 ; Gupta etA al. , 2005 ) , Parkinson ‘s disease ( PD ; Yasui etA al. , 1992 ) , and amyotrophic sidelong induration ( Kurland, 1988 ) .1.4 How are worlds exposed to aluminium?There are several avenues which worlds can be exposed to aluminium due to its natural copiousness in the environment. Traces can be found in nutrient, H2O and air and even more sums can be intentionally introduced by worlds ( Miller et al. , 1984 ; Cech and Montera. , 2000 ; Lettermann and Driscoll. , 1988 ) . Aluminium compounds can be found in pharmaceuticals like alkalizers, anodynes and antiperspirants. They are besides used in H2O intervention processes as coagulators and can even be fou nd as metal in mundane consumer merchandises like foil paper and take away nutrient boxes. Aluminium compounds are besides found in about all workss. Edible workss that are of course high in aluminum include murphies, Spinacia oleracea and tea foliages ( WHO, 1998 ) . A recent survey at Keele University besides warned that unnecessarily high sums of aluminum are being used in the fabrication of baby powdered milk and that the aluminum content of expressions prepared from powdery milks was significantly higher than ready-made milks, ensuing in babies consuming up to 600 I?g of aluminum per twenty-four hours Exley and Burrell, 2010. Pregnant adult females may be potentially exposed to aluminium through the diet ( including imbibing H2O ) , dust and dirt consumption and some medicines ( Roig et al. , 2006 ) . Surveies have proven that aluminum is a major subscriber to pathologies such as dialysis dementedness, iron-adequate microcytic anemia, osteomalacia ( [ Suwalsky et al. , 2004 ] a nd [ Domingo, 2006 ] ) Over the past 40 old ages the controversial inquiry refering the possible function for aluminium neurotoxicity in lending to the pathogenesis of Alzheimer ‘s disease has been debated but remains unsolved.hypertext transfer protocol: //www.sciencedirect.com/science? _ob=ArticleURL & A ; _udi=B6TCN-4P6VDVC-2 & A ; _user=128592 & A ; _coverDate=10 % 2F08 % 2F2007 & A ; _rdoc=1 & A ; _fmt=high & A ; _orig=gateway & A ; _origin=gateway & A ; _sort=d & A ; _docanchor= & A ; view=c & A ; _acct=C000010620 & A ; _version=1 & A ; _urlVersion=0 & A ; _userid=128592 & A ; md5=ab46010ee2e9fa0fa7782f2dba6ebd0e & A ; searchtype=a1.5 What do we already know about aluminum and seminal fluidSo far I have found out that although aluminum is largely a harmful metal with no direct biological benefit ( Yokel, 2002 ) , it is found in copiousness in our environment. ( Martin, 1997 ) .Aluminium in high concentrations was linked to reduced sperm motility ability ( Hovatta et al. , 1998 ) . It is besides responsible for impaired sperm quality. Research was undertaken to detect the underlying disagreements between sperm quality and geographic location by Hovatta and co-workers. Due to miss of elucidation as to factors doing the diminution, surveies to analyze seeds quality and the concentrations of aluminum, Cd and lead in sperm cell and seminal plasma in a group of employees of a refinery and a polyolefin mill and the consequences were compared with informations obtained from samples from sperm bank seeds quality ( Hovatta et al.,1998 ) . The survey discovered that the average sperm concentrations were similar in the mill employees ( 96H106/ml ) . The sperm giver campaigners of the comparing group had a important difference of ( 104H106/ml ) in 352 giver campaigners at the sperm bank of the Family Federation of Finland ( 107H106/ml ) between May 1993 and May 1995 ( Hovvatta et al. , 1998 ) . Research done in Finland discovered that high and unchanged sperm counts have been found ( Suominen and Vierula, 1993 ; Vierula et al. , 1996 ) . In contrast to that, two necropsy series of middle-aged Finnish work forces showed an addition in the incidence of upsets of spermatogenesis between the old ages 1981 and 1991 was unveiled ( Pajarinen et al. , 1997 ) . Meanwhile, decreased birthrate in Britain ran parallel with that in Finland, based on differences in the clip to construct ( Joffe, 1996 ) . Regional differences were besides apparent in the USA, with the highest mean sperm concentration being found in New York ( 131.03106/ml ) and ( A © European Society for Human Reproduction and Embryology ) 115 the lowest in California ( 72.73106/ml ) ( Fisch et al. , 1996 ) . A little addition in sperm concentration between the old ages 1972 and 1993 was seen in Seattle, Washington ( Paulsen et al. , 1996 ) . It has been suggested that environmental factors played a function in the diminution observed in Europe, particularly environmental oestrogens ( Sharpe and Skakkebaek, 1993 ) . Oestrogens have besides been suggested to hold caused the addition seen in the incidence of cryptorchidy and testicular malignant neoplastic disease ( Sharpe and Skakkebaek, 1993 ; Skakkebaek and Keiding, 1994 ) . Heavy metals are potentially pollutants that may be harmful to sperm production. Exposure due to business or geographics to several metals is known to impair sperm quality ( Schrag and Dixon, 1985 ) . Substances such as lead and Cd concentrations have been measured in human seeds, seminal plasma, sperm cell, blood and piss, and high concentrations have been found to be related to impaired sperm quality ( Lancranjan et al. , 1975 ; Plechaty et al. , 1977 ; Braunstein et al. , 1978 ; Pleban and Mei, 1983 ; Stanwell-Smith et al. , 1983 ; Thomas and Borgan, 1983 ; Saaranen et al. , 1987, 1989 ; Chia et a l. , 1992 ; Hu et al. , 1992 ; Xu et al. , 1993 ) . In several experiments, many metals have besides been shown to be harmful with respect to testicular map and sperm production ( Alabi et al. , 1985 ) . Aluminum may good be one of the possible pollutants, because it reduces the weight of the testicles and was seen to do reduced epididymal sperm counts in the mouse ( Llobet et al. , 1979 ) . When aluminum is ingested in big sums, it leads to accumulation in certain mark variety meats such as the homo and animate being testicular tissues which consequences in harm occurring. The of long-run ingestion of aluminum showed suppressive effects on sexual behavior, lessening in birthrate and aggressive behavior ( Bataineh et al. , 1998 ) . There is grounds implicating androgenic endocrines involved in mechanisms of aluminum toxicity on male reproduction ( Sharpe, 1990 ) . To add to that, Guo et Al. ( 2005a ) carried out trials that proved that aluminium disposal significantly increased azotic oxide ( NO ) production and decreased both testicular adenosine 3aˆ?,5aˆ?-cyclic monophosphate ( camp ) and testosterone degrees. They demonstrated that inordinate NO activated inducible NO synthase ( NOS ) which may be involved in generative toxicity of aluminum. Information refering the generative toxicity and testicular disfunction of aluminum still needs more research. Besides, the function of propolis against aluminum induced impairments in the generative ability of rats has non yet been discovered. The survey taken on by ( Yousef and Salama,2009 ) , was aimed at finding the generative toxicity of aluminum chloride in grownup male rats. It showed that aluminum enhanced lipid peroxidation in plasma, testicles, encephalon, kidney, lung and liver of coneies, and besides in civilization of coney sperm ( [ Yousef, 2004 ] , [ Yousef et al. , 2005 ] and [ Yousef et al. , 2007 ] ) . Besides, to measure the protective consequence of propolis against the possible testicular disfunction caused by aluminum chloride. Table 1. Relative weights ( g/100A g organic structure weight ) of sex variety meats of male rats treated with AlCl3, propolis and AlCl3 + propolis.ParameterExperimental groupsControlAlCl3PropolisAlCl3+PropolisTestiss 0.72A A ±A 0.093 0.58A A ±A 0.061** 0.78A A ±A 0.0739*** 0.66A A ±A 0.091* Seminal cyst 0.35A A ±A 0.061 0.20A A ±A 0.081** 0.39A A ±A 0.105*** 0.31A A ±A 0.119* Epididymis 0.27A A ±A 0.036 0.19A A ±A 0.037** 0.30A A ±A 0.036*** 0.24A A ±A 0.041* Prostate gland 0.16A A ±A 0.023 0.14A A ±A 0.021 0.16A A ±A 0.017 0.15A A ±A 0.02 Full-size tabular array Valuess are expressed as meansA A ±A SD ; nA =A 10 for each intervention group. Significant difference from the control group at **PA & lt ; A 0.01. Treatment of male rats with AlCl3 significantly ( PA & lt ; A 0.01 ) decreased sperm concentration and motility rate. Meanwhile increased dead and unnatural sperm, as compared to command and propolis groups were seen in Table 2. Treatment with propolis entirely showed no important effects on sperm concentration and motility. while caused important ( PA & lt ; A 0.05 ) lessening in dead and unnatural sperm compared to command group. On the other manus, intervention with propolis in combination with AlCl3 caused significantly alleviated the diminution in sperm concentration and motility, and significantly decreased the per centum of dead and unnatural sperm compared to AlCl3 group. This means that propolis minimized the toxicity of AlCl3.ignificant difference from the AlCl3-intoxicated group at # PA & lt ; A 0.05 and # # PA & lt ; A 0.01. Table 2. Changes in sperm concentration ( Sp. Conc. , A-106/ml ) , motility ( % ) , and dead ( % ) and unnatural ( % ) sperm of male rats treated with AlCl3, propolis and AlCl3A +A propolis.ParameterExperimental groupsControlAlCl3PropolisAlCl3 + PropolisSp. Conc. 212A A ±A 15.5 148A A ±A 8.1** 233A A ±A 12.1 # # 199A A ±A 7.5 # # Motility 72.4A A ±A 1.89 50.9A A ±A 2.64** 79.7A A ±A 1.64 # # 70.5A A ±A 1.43 # # Dead 25.2A A ±A 1.95 45.1A A ±A 2.21** 20.2A A ±A 1.78* # # 28.8A A ±A 3.01 # # Abnormal 14.6A A ±A 1.96 21.3A A ±A 2.312** 11.6A A ±A 1.27* # # 16.7A A ±A 1.337 # # Full-size tabular array Valuess are expressed as meansA A ±A SD ; nA =A 10 for each intervention group.Significant difference from the control group at *PA & lt ; A 0.05 and **PA & lt ; A 0.01.Significant difference from the AlCl3-intoxicated group at # PA & lt ; A 0.05 and # # PA & lt ; A 0.01. This survey observed the consequence of aluminum chloride on sperm motility. ( Table 2 ) . Additionally, Dawson et al. , 1998 E.B. Dawson, S. Ritter, W.A. Harris, D.R. Evans and L.C. Powell, Comparison of sperm viability with seminal plasma metal degrees, Biol. Trace Elem. Res. 64 ( 1998 ) , pp. 215-223.Dawson et Al. ( 1998 ) found that high concentrations of aluminum in human sperm cell and seminal plasma are correlated with reduced sperm motility and viability. Motility is important in enabling the sperm to swim through the female generative piece of land and make the egg cell to accomplish fertilisation ( Aitken, 1995 ) . The observation can be concluded by stating that the lessening in sperm motility was caused in portion to the attendant decrease in testosterone production ( [ Guo et al. , 2005a ] and [ Yousef et al. , 2005 ] ) following aluminum intervention. Table 3. Plasma testosterone concentration ( ng/ml ) and activity of testicular 17- ketosteroid reductase enzyme ( U/min/mg protein ) , and testes protein content ( mg/g tissue ) of male rats treated with AlCl3, propolis and AlCl3 + propolis.ParametersExperimental groupsControlAlCl3PropolisAlCl3 + PropolisTestosterone 1.31A A ±A 0.244 1.00A A ±A 0.115* 1.51A A ±A 0.113* # 1.15A A ±A 0.064 # 17-Ketosteroid Reductase enzyme 14.6A A ±A 2.02 10.2A A ±A 1.13** 19.1A A ±A 1.49** # # 12.8A A ±A 2.03* # Protein content 76A A ±A 4.4 60A A ±A 4.7** 105A A ±A 5.3** # # 75A A ±A 5.2 # # Full-size tabular array Valuess are expressed as meansA A ±A SD ; nA =A 10 for each intervention group.Significant difference from the control group at *PA & lt ; A 0.05 and **PA & lt ; A 0.01.Significant difference from the AlCl3-intoxicated group at # PA & lt ; A 0.05 and # # PA & lt ; A 0.01. Datas in Table 3 showed important lessening in plasma testosterone concentration ( PA A 0.05 ) and testicular protein ( PA A 0.01 ) in rats treated with AlCl3 compared to command. While, propolis significantly increased testosterone and protein content and alleviated the negative effects for AlCl3 in group 4 on these parametric quantities. Aluminium chloride exposure displayed gonadotoxic effects in male rats and maternal decease was associated with foetal decease in pregnant rats. The exposure to aluminum increases the incidence of fetal abnormalcies in rats and mice ( Belles et al. , 1999 ) . The survey of Guo et Al. ( 2005a ) demonstrated that exposure to aluminium lowered plasma and testicular testosterone degrees in mice. It was suggested that the terrible decrease in male libido and birthrate following the aluminium disposal might be a consequence from inordinate aluminum accretion in the testicles and low testosterone concentrations. High degrees of aluminum in aluminium-treated mice were evident at hebdomad 3 before the effects on male libido and birthrate manifested. The disagreement was reasoned such that aluminium accretion failed to instantly impact the enzymes for androgen biogenesis or bring forth a possible perturbation in hypothalamic-pituitary-gonadal axis. However, the present survey showed that AlCl3 caused important diminution in the activity of 17-ketosteroid reductase after 70A yearss intervention ( Table 3 ) . Table 4. Changes in the activities of catalase ( CAT ; mol/h/g tissue ) and glutathione S-transferase ( GST ; I?mol/min/g tissue ) , and the degrees of thiobarbituric acid-reactive substances ( TBARS ; nmol/g tissue ) and reduced glutathione ( GSH ; mM/g tissue ) in testicles of rats treated with AlCl3, propolis and AlCl3A +A propolis.ParameterExperimental groupsControlAlCl3PropolisAlCl3+PropolisCat 6.96A A ±A 1.140 3.01A A ±A 0.578 ** 9.95A A ±A 1.050 ** # # 5.89A A ±A 0.793 # # GST 1.08A A ±A 0.100 0.59A A ±A 0.154** 1.43A A ±A 0.299 ** # # 0.96A A ±A 0.125 # # TBARS 71.8A A ±A 5.58 195.9A A ±A 10.62 ** 60.4A A ±A 6.18 * # # 97.4A A ±A 9.58 * # # GSH 6.02A A ±A 0.694 4.15A A ±A 0.690 * 8.25A A ±A 0.902 * # # 5.74A A ±A 1.863 # Full-size tabular array Valuess are expressed as meansA A ±A SD ; nA =A 10 for each intervention group.Significant difference from the control group at *PA & lt ; A 0.05 and **PA & lt ; A 0.01.Significant difference from the AlCl3-intoxicated group at # PA & lt ; A 0.05 and # # PA & lt ; A 0.01. The control testicles are surrounded by a dense hempen tissue capsule known as the adventitia albuginea The histological survey showed that.The testies are divided into lobules by thin hempen septa ; the interstitial tissue surrounds the lobules which contain several seminiferous tubules within them. The tubules are lined with germ cells in assorted phases of spermatogonia, some primary and secondary spermatocytes, spermatids and mature sperm cell that occupy the Centre of the tubule. Between the spermatogonia and the balance of the basal lamina are the sertoli cells. The interstitial tissue is supported by Leydig cells in chief. They occur singly or in bunchs and are embedded in the rich rete of blood and lymph capillaries. Observations of testicles treated with AlCl3 revealed several changes. The accretion of exfoliated source cells within some seminiferous tubules affected their architecture and left them disorganized. Some tubules exhibited ripening apprehension. And moreover, so me source cells had little and darkly stained nuclei. Marked dilation and congestion of blood vass were noticed in the interstitial infinites. Hyperplasia of Leydig was detected in the interstitial tissue. The Leydig cells became crowded and formed dense bunchs that surrounded most of the seminiferous tubules ( Fig. 2 ) . Some subdivisions of testicles of the rats treated with propolis entirely showed that they were less or more similar to the control subdivisions ( Fig. 3 ) . Testis of rats treated with aluminium plus propolis revealed that it regained about all of its original construction and singular Restoration of the normal image of seminiferous tubules was attained. The germ cells appeared regular in form with disappearing of most cytoplasmatic vacuolization. Most of the karyon became vesicular ( Fig. 4 ) . Testes accumulate high aluminium over age in rats ( Gomez et al. , 1997 ) . Light microscopy of silver-stained paraffin subdivisions of the testicles demonstrated legion i ntracytoplasmic black-stained all right farinaceous inclusions in Leydig cells ( Reusche et al. , 1994 ) . The histological alterations in testicles of rats treated with AlCl3 ( Fig. 2 ) is coincident with the obtained informations by Khattab ( 2007 ) who studied the consequence of AlCl3 on the testicles of rats after an intraperitoneal injection was administered. The testicles showed histological disturbance including terrible harm within the seminiferous tubules and vascular devolution on the spermatogenic and sertoli cells cytol. The originative epithelial tissue of the seminiferous tubules was thinner in topographic points and spermatids became really scarce in presence. Sperm Numberss was low and there were no sperm in the lms. Besides, up on negatron microscopic surveies, in the aluminium-treated group, there were some anomalousnesss in the atomic membrane, amendss to some chondriosomes, ribosomes population lessening, and an addition in the figure of lysosomes in the sertoli cell cytol. In the primary spermatocyte cytol, there was an addition in the unsmooth endoplasmic Reticulum. Guo et Al. ( 2005b ) found that after 2 hebdomads of aluminum intervention, hurtful effects and histopathological alterations of testicular tissues were observed. However, noticeable spermatogenetic loss was viewed as necroses in the spermatids and sperm cell in aluminium-treated group at hebdomad 5. The damage caused by aluminum was accompanied chiefly by the drawn-out accretion of aluminum in the mice testest. Fig. 1.A Photomicrograph of control testicle subdivision demoing interstitial cells ( I ) and germ cells ( G ) . H & A ; E discoloration ( 400A- ) . Fig. 2.A Photomicrograph of testicle subdivision that treated with aluminum demoing germ cells ( G ) , exfoliated source cells ( E ) , hyperplasia of Leydig cells ( I ) and vacuolization ( V ) . H & A ; E discoloration ( 400A- ) . Fig. 3.A Photomicrograph of testicle that treated with propolis demoing germ cells ( G ) . H & A ; E discoloration ( 400A- ) . Fig. 4.A Photomicrograph of testicle subdivision that treated with Aluminium and propolis demoing germ cells ( G ) . H & A ; E discoloration ( 400A- ) .1.6 Purposes and aims of my undertakingIn this undertaking my chief purpose was to find the presence of aluminum in seminal fluid and sperm cell. I had to found out if aluminum was present in the seminal fluid or the sperm cell.DiscussionTHE EFFECT OF ORAL HIGH ALUMINIUM INTAKE ONRAT SPERMATOGENESISI.M.D. Rashidi. Head of section & A ; member of adept commission Dept of pathology Medical school Ahwaz medical university, Ahwaz Iran Aluminum is one of the most abundant elements in the Earth crust and enters to the organic structure through imbibing H2O, foods and drugs like antacids. Aluminium poising causes broad scope of upsets, including: a lessening in the release of neurotransmiters and suppression of electromotive force dependent Ca channels. The function of Ca on GnRH release and its action is detected so, in this perusal, the consequence of high aluminum consumption on rats spermatogenesis is investigated. The experiment performed in four groups, a control group and three experimental groups consumed 0.625, 1.25 and 2.5 milligram aluminum per gm diet for 60 yearss. Epididymis and vessel deferens were dissected cut and diluted with normal salin. In all groups weight of vessel deferens, epididymis, testicle and whole animate being, sperm count per gm deferens and epididymis tissues were determined so, the testicular tissues fixed in formol for survey of histopathology. The consequences have shown that in experimental groups which consumed 1.25 and 2.5 milligram aluminum per gm diet, the vessel deferens, epididymis, testicle and carnal weight were significantly decreased. In this animals the figure of sperm per gm tissues from vessel deferens, epididymis were reduced. The ripening apprehension is seen in seminoferous canal and it have n't spermatogenesis. Therefore, this analyzing indicated that high aluminum consumption in rat have an suppressing consequence on spermatogenesis and this consequence is dose dependant. hypertext transfer protocol: //www.sciencedirect.com/science? _ob=MImg & A ; _imagekey=B6TCR-4CB7K82-GF-1 & A ; _cdi=5177 & A ; _user=128592 & A ; _pii=S0378427403904048 & A ; _origin=gateway & A ; _coverDate=09 % 2F28 % 2F2003 & A ; _sk=998559999.8998 & A ; view=c & A ; wchp=dGLzVtb-zSkzV & A ; md5=1f1a3377fb5ad50ff2bd8ffd8947d810 & A ; ie=/sdarticle.pdf Read and summarize but cite hypertext transfer protocol: //humrep.oxfordjournals.org/content/13/1/115.full.pdf

How Did Penicillin Help the Allies Win Wwii?

How did Penicillin help the Allies win WWII? Branna Prine Word Count: 1,894Table of Contents Plan of the Investigation†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 3 Summary of Evidence†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ 4-5 Evaluation of Sources†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ 6 Analysis†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦. 7-9 Conclusion†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 0 Bibliography†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ 11 A. Plan of the Investigation The scope of the investigation concerned the magnitude of penicillin and how it helped the allies win World War II (WWII). The researcher scrutinized the invention and process in which penicillin came to be, the different types of penicillin we have and use today, how it was used to help us more than any other drug in history at one point, and how it came to save thousands of lives in WWII. The researcher’s method was to use multiple primary resources such as articles written by scholars, medical professionals, and historical investigators. The evidence that was found was evaluated and observed for origin, value, and purpose of penicillin and its use in WWII. B. Summary of Evidence In 1928, Sir Alexander Fleming discovered the first natural mold of Penicillin(Tames 5). Even though his â€Å"creation† was mostly on accident, Fleming had been itching to discover a new â€Å"wonder drug† since he first became interested in being a scientist(5). Though the knowledge of disease causing bacteria was somewhat understood at the time, medical researchers had yet to find a chemical able to rid the body of the potent bacteria while not harming the body at the same time. Fleming’s first form of Penicillin was just what was needed to kick off the ultimate breakthrough of medicine. Even then, it wasn’t until another decade after this discovery that people really started needing and using Penicillin to save lives(History of Penicillin). Although Fleming is credited with this important discovery, it took the start of WWII to pursue medical scientists to strengthen the effect the drug had on people. It’s all thanks to a total of 39 different groups of scientists that hundreds of thousands of fighting men’s lives were saved(World War II and Peoria). Penicillin was considered to be the war’s official wonder drug because of the unbelievable effects it had on infections and deadly diseases. The use of this drug is what made WWII different from any previous war(World War II and Peoria). Before Penicillin was introduced to the allies of the war, soldiers rapidly died from infections such as Staphylococcal(staff), streptococcal(strep), and pneumococcal(pneumonia) (World War II and Peoria). Since death was the ultimate outcome of these infectious diseases, the number of available soldiers to fight dropped immensely and expeditiously. Due to the shortage of men, sergeants called for men to be recruited no matter their experience; as long as they were 18 years old(Inside WWII). That then led to more deaths of young cadets because of the lack of knowledge of what to do on the battle field. At that point of time, the allies came to the conclusion that what they needed was a wonder drug ready to use when needed. That’s when Howard Florey and Ernst Chain were forced in with their team of scientists to use Fleming’s Penicillin mold and improve it to where it cured a grown man of a life threatening infection or disease; and make a quantity of hundreds of thousands(World War II and Peoria). After a total of 39 separate drug laboratories in the U. S. ad given their all to synthesize inorganic Penicillin, in 1941, they created a version 20 times more potent than what they started out with in 1939(22). By the autumn of 1943 the war doctors were using the drug on only American and Allied military patients with life-threatening infections. Since a single infection usually called for two million units of Penicillin(single ampoules held 100,000 units), rati oning who got what treatment was crucial(World War II and Peoria). The scientists shortly discovered that, while the new version of Penicillin was of very good quality, their new focus needed to be directed on quantity of the drug. By 1945, the team of scientists brilliantly came up with an amazingly effective technique that supplied the allies with 7,952 billion units of the strongest possible version of penicillin at the time(World War II and Peoria). Though the injections were painful(the needles had to be large enough to allow the medicine to flow through) and had to be given every four hours, soldiers agreed it was worth being able to live and continue fighting to the victory of WWII(23). By the end of it all, the magnificent wonder drug saved the lives of hundreds of thousands of warriors and even more citizens in the U. S. and has continued to fulfill its duty all the way up to today’s time(World War II and Peoria). C. Evaluation of Sources â€Å"World War II and Peoria† was the title of the article that helped the researcher the most to come to a conclusion on how Penicillin helped the allies win WWII. The article’s purpose was to further inform people about the studies and development of penicillin during WWII. The article talked about the illnesses and wounds the soldiers fighting in WWII came in contact with and how Penicillin helped them fight and survive through it all. This particular unit differed from the rest because it did not have its focal point on how Penicillin came to be, but rather its purpose and usage in WWII. However, it did have some limitations of information on specific numbers and names of soldiers that were affected by the wonder drug. The point of view that the article used was from a college professor who had dabbled in history as well as medicine. The professor’s name was Jennifer Rosenburg and she had posted this information around 2000. The second most helpful article’s title was â€Å"Inside WWII . The purpose of the article being written was to tell a more medical side of the war as opposed to the blood and guts. Although, it still lingered on with the facts and details of the war itself too much, which limited it with important details it should have withheld about the medical side of the war. But, because of the focusing on one little part at a time problem, the researcher ended up to find it very valuable. It stated facts that were focused on the medicine during the war instead of the medicine in general. The origin of this information was found by Dr. Steven Lister. He was a doctor during the war, so this gave him a personal experience and the researcher found great value in this type of first hand information. D. Analysis During the period of penicillin gaining importance, World War II was going on. This specific war was fought from 1939 to 1945 by the Axis: Germany, Italy, and Japan; and the allies: Australia, Belgium, Brazil, Canada, China, Czechoslovakia, Denmark, Estonia, France, Greece, India, Latvia Lithuania, Malta, The Netherlands, New Zealand, Norway, Poland, South Africa, United Kingdom, United States, USSR, Yugoslavia, and many others(The Axis and the Allies). The war was fought by more than fifty countries in the world. The main causes of the war for the U. S. and Britain were The Great Depression and the Treaty of Versailles(Wars and Battles 1939-1945). Around 1943, the Allies really started to need help because they were losing so many soldiers due to infections caused mostly by severe battle wounds which ultimately led to the being outnumbered and overtaken by the Axis. That is where Penicillin came in. Scientists spent over $2,000,000 trying to perfect and learn more about the drug(World War II and Peoria). They eventually found out that what this drug did, once successfully inserted in the body, was it located the source of the infection and fought only the harmful bacteria( Tames 15). As opposed to the other drugs, at the time, which destroyed not only dangerous bacteria, but the vital bacteria used for fighting infections naturally found in the body(16). The drug, therefore, saved over hundreds of thousands of men(World War II and Peoria). A few months after the Allies received the drug, the Axis groups started to surrender, which officially ended the war in 1945 with the Allies‘ being the victorious group(Wars and Battles 1939-1945). Under the circumstances that the allies started winning after penicillin came into the picture, that was considered to be one of the main, but least recognized, expositions for the victory of the allies. Of all the evidence the researcher has came up with to support this claim, the three main pieces of evidence are as follows: only two years after penicillin was thoroughly introduced to the war, the allies won; so many lives were saved –on and off the battlefield–how could it not have such a huge impact; and they must have known it was going to be a huge help, otherwise they would not have invested so much money in the whole process of innovating and testing the drug(World War II and Peoria). The first point was the victory of the allies shortly after penicillin came to use in the war. When they fought without the drug, the allies were losing by a drastic amount considering the vast number of men that died every day from infections on their battle wounds and had suffered without the care that penicillin provided(23). The soldiers suffered for a total of about three and a half years before they actually got penicillin shipped in that had an affect on people(World War II and Peoria). However, when they did get the wonder drug in, they spent about six months learning the different side effects, insertion ways, and preparations needed before they gave the soldiers all they needed to keep them alive and fighting(World War II and Peoria). The second point, was that there was such a large number of people saved by the drug, that it had to have made some kind of a difference in the way World War II ended. In less than a year, penicillin saved 187 lives just of people in America(21). In the war, penicillin took the death toll, caused by wound infections, from over 12 percent down to less than 1 percent on average(23). That would mean the allies side of the war would have had a 12 percent advantage over the axis in the battle at this time due to the drug keeping the soldiers dying from wound related infections. The last point stated was with all the time, money, and dedication with bettering this drug, penicillin obviously had a huge impact on World War II The U. S. spent over $2,000,000 trying to perfect the drug to make it effective enough to cure a whole army of men versus enough for one or two individual people. The money not only paid for the equipment needed, but for the 39 different groups of scientists hired to innovate and test the drug to reach the desired goal(History of Penicillin). E. Conclusion When Penicillin started out, it was but a simple form of mold. Then, When Fleming discovered it destroyed bacteria in the human body without harming the human in any way. He then had over 30 different teams of scientists work at improving this mysterious new drug to make it potent enough to help a man overcome pneumonia. After years and years of experiments and millions of dollars spent, they finally got what they had been working for. They sent as much as they could to the troops fighting WWII at the time. The doctors at the war stations gave it to the men in critical condition and the drug got them back on their feet and fighting in about a week. F. Bibliography Works Cited â€Å"The Axis and the Allies. † The Countries Who Fought in World War Two. Mandy Barrow, 2010. Web. 12 Nov. 2011. . â€Å"The Drug Safety. † The Drug Safety. The Drug Society, 2011. Web. 26 Sept. 2011. . â€Å"How Penicillin Came to Be. Alexander Fleming in WWII. J. Miller. Web. 28 Sept. 2011. . â€Å"Inside WWII. † History Learning Site. Chris Trueman, 2000. Web. 28 Sept. 2011. . Prine, Patricia R. â€Å"Moma's Notes. † Personal interview. 2 Oct. 2011. Tames, Richard. Penicillin: a Breakthrough in Medicine. Chicago: Heniemann Library, 2001. Print. â€Å"Wars and Battles, 1939-1945. † United States American History. Web. 12 Nov. 2011. . â€Å"World War II and Peoria. † 20th Century History. Jennifer Rosenburg, 2001. Web. 26 Sept. 2011. . â€Å"WWII and Medicine. † Medicine in World War II. 2001. Web. 27 Sept. 2011. .

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English - Essay Example Even as my father held the bicycle seat straight for me as I learned how to pedal fast in order to find my center of gravity, I could not help but meet a few mishaps along the road to what I perceived to be travel independence at that time. It was not uncommon for me to go out with my father for a lesson and practice run in my two wheeled bit and then return with a few scrapes on the knees and elbow areas. After all, learning to ride a bike entailed some lessons that were designed to help me learn how to be a safe and accident free bicycle rider. All of the experiences that I had during the time that I was learning how to ride my bicycle helped me to become a very safe and responsible cyclist when I finally got up enough courage and guts to begin riding my bike to school. I remember that my parents were quite apprehensive about letting me ride alone on the day that I announced I was ready to take my bicycle to school without any back up from my father. What if, my mother thought, I lost control of the bicycle on the side walk and I ended up rolling into the main road? Who would stop my bicycle from veering onto the wrong path? What if I suddenly lost control of the bicycle? Who would grab the bike seat in order to keep me steady on it? What if... what if... I told my mother not to worry. I would not have decided to finally take my bicycle to school if I did not feel like I could take on the challenges that beset a cyclist on the way to school. Years later, I would be facing my parents with yet another request for a far more independent mode of transportation. I was now old enough to apply for a student permit that would allow me to enroll in driving school and allow me to drive in most areas provided I did so with a licensed driver in the front seat. Needless to say, my parents, my mother in particular was even more petrified at the thought allowing me to have not only access to the family car, but

The Life and Music of Johann Strauss II Essay Example | Topics and Well Written Essays - 750 words

The Life and Music of Johann Strauss II - Essay Example From among the hundreds of musical compositions that Johann Strauss II created, his most famous work was identified to be the Blue Danube, categorized as â€Å"the most widely played and arranged pieces of its time, known to the most casual listener today from many radio, film and television uses of it†. A countdown of his musical scores generated this profile: â€Å"150 waltzes, one hundred polkas, seventy quadrilles (square dances), mazurkas (folk dances from Poland), marches, and galops (French dances)†. Johann was noted to be the king of waltz or the waltz king.His music was also noted to belong to the classical genre and assuming the orchstral and opera style. In fact, a total of more than 500 orchestral compositions were attributed to his name. Likewise, Johann Strauss II was known to have popularized both light music and dance music, both musical genres and styles that gave way to less serious form of classical music intended for an audience for the purpose of da ncing the waltz, or to put them in the right mood to listen to a concert-type of music. Since Johann’s compositions were predominantly orchestral or opera in style, the musical accompaniment was composed of a variety of musical instruments chosen appropriately to create the intended mood: for dancing, for easy listening, to appreciate a particular musical instrument: cello, the piano, or the whole orchestra. He has also composed selections of best classical music of his time; concert music, music of the opera, and favorite dance music attributed to the Strauss family, to name just a few.From among the famous operettas noted to be composed by Johann Strauss II, the following were detailed: â€Å"Die Fledermaus, is probably one of the greatest operettas ever written and a masterpiece of its kind. The lovely Du und Du waltz is made up of excerpts from this work. His two other most successful operettas were A Night in Venice (1883), from which he derived the music for the Lagoon Waltz, and The Gypsy Baron (1885), from which stems the Treasure Waltz†.... Music of Johann Strauss II From among the hundreds of musical compositions that Johann Strauss II created, his most famous work was identified to be the Blue Danube (An der schonen blauen Donau), categorized as â€Å"the most widely played and arranged pieces of its time, known to the most casual listener today from many radio, film and television uses of it† (Rovi Corp, 2013, par. 1). A countdown of his musical scores generated this profile: â€Å"150 waltzes, one hundred polkas, seventy quadrilles (square dances), mazurkas (folk dances from Poland), marches, and galops (French dances)† (Encyclopedia of World Biography, 2013, par. 9). Johann was noted to be the king of waltz or the waltz king (The Johann Strauss Society of Great Britain, 2013; Encyclopedia of World Biography, 2013). His music was also noted to belong to the classical genre and assuming the orchstral and opera style (Rovi Corp, 2013). In fact, a total of more than 500 orchestral compositions were attrib uted to his name (The Johann Strauss Society of Great Britain, 2013). Likewise, Johann Strauss II was known to have popularized both light music and dance music, both musical genres and styles that gave way to less serious form of classical music intended for an audience for the purpose of dancing the waltz, or to put them in the right mood to listen to a concert-type of music. Since Johann’s compositions were predominantly orchestral or opera in style, the musical accompaniment were composed of a variety of musical instruments chosen appropriately to create the intended mood: for dancing, for easy listening, to appreciate a particular musical instrument: cello, the piano, or the whole orchestra. He has also composed selections of best classical music of his time; concert music, music of the opera, and

Discretionary Benefits within the Manufacturing Industry Research Paper

Discretionary Benefits within the Manufacturing Industry - Research Paper Example ufacturing businesses and other productive industries in turn offer fringe benefits to their employees to boost their confidence, morale, dedication and commitment (‘affective and normative’) (Aldag and Reschke, 1997). As a result, workers are keen to work better for their employers to ensure accomplishment of goals and targets. (Daft, 2009) and (Kreitner and Kinicki, 2007) The Industry that has been chosen by the researcher for this analysis is US Airline Industry. Indeed, US airline travel industry is one of the largest industries (comprising low cost barriers, regional, national and international airlines) within United States that has been offering its services daily to millions of travellers, visitors, students, business personnel and government officials. This industry provides direct and indirect employment to millions of personnel thereby contributing in USA’s economic well-being, growth and sustainability. US Airways, United Airlines, Continental Airlines, Delta, Northwest and other airlines are among the major players. Foreign airlines also offer their travel services in USA. (ZACKS Report, 2010) The benefits offered by employers are divided into two main types namely Monetary Payments (in exchange for services offered) and Discretionary Benefits (they are optional or not mandatory for the producer) to their employees. This paper will throw light over the discretionary or optional benefits offered to workers in the manufacturing industry. There are three major types of discretionary benefits namely Workers’ â€Å"Protection Programs, Paid time-offs, Accommodation and Employee Skills development programs† (Martocchio). This paper will discuss in detail each of the above mentioned benefits to employees, will demonstrate any factors that may influence these benefits within the chosen manufacturing industry and will end up on recommendations that could be used to improve current practices and benefits. (Daft, 2009) The very first discretionary

What's Complicating Bernanke's Balancing Act by James Cooper Essay

What's Complicating Bernanke's Balancing Act by James Cooper - Essay Example The Federal Reserve was created to guide the nation towards a stable financial system. It's goal is to maintain stable prices, low inflation, and moderate long term-interest rates. Keeping inflation low though monetary policies is one of the ways to ensure a stable economic preformance. The article also talks about how proposed protectionist policies threaten to increases overall inflation. The author believes that present interest rates are too low, and that globalization makes it harder to determine the right interest rates to promote economic growth. Usually, high demand for goods and services would result in increased interest rates by the Federal Reserve to slow down demand and thus curb inflation. This is appropriate if the demand exceeds economic ability to produce those goods and services. However, a global market changes the dynamics of traditional economic systems, giving the Federal Reserve less control over the economy. Indeed, prices of goods and services are determined by overseas market factors aside from those in the United States. The issue of globalization, which is the expansion and growth of international economic activity, has always been a fiercely debated issue. It is a complex process operating in various levels which can lead to increased competition, government borrowing, trade, etc. These factors have variable effects depending on the government's policies and management. The author's conjecture is that globalization resulting into an "interdependency" among economies will help prevent an economic crisis in the United States from happening (although the dollar could weaken due to the economic success of other foreign currencies). I agree. Nations are turning into one global network where standards of living depend on the value added to that network. It brings about gains thorough consumption and exchange between the nations involved. A significant amount of economic growth seen in the late 20th century is owed much to globalization and the free trade. One of it's drawbacks however, is the imbalance in world trade. Article 2: "U.S.: The Double Whammy That Could Ignite Inflation" by James Cooper, March 20, 2006 in BusinessWeek Online The article talks about how the decrease in productivity together with the rise of labor costs could potentially hike up inflation at economically debilitating levels. Last year, productivity increased-a good performance, considering the economy was weak during the year's end. However, the growth rate has progressively declined over the past three years, which is not a good sign. The correlation between labor costs and productivity was also explored in the article: the increase in labor compensations has slowed productivity, and the trend is likely to continue. Typically, productivity helps offset labor costs. However, if productivity is low, companies will be forced to raise prices to compensate and keep profits healthy. As such, this will affect Federal Reserve decisions regarding interest rates. The Federal Reserve can help curb inflation levels by imposing higher interest rates to lessen demand and stabilize economic performance. Economists concur that an economy will be better off if inflation is low, thus economic policies should aspire for stability in prices. A fast growth without inflation could be possible with higher productivity, and the author postulates that this is could be done through companies' utilization of technological innovations. For the most part, I agree with this conjecture. The issue about technological and economic changes is not new. Innovations in the Industrial Revolution caused a huge leap

Immigration and unemployment in canada Term Paper

Immigration and unemployment in canada - Term Paper Example he above figure shows that although Canada has been accommodating immigrants since the late 19th century, yet the number has drastically increased after the mid of the 20th century, specifically in the last two decades. (www.immigrationwatchcanada.org, 200-) mentioned in the same report that recent surveys have discovered that over 2 millions of Canadians are unemployed. The point of consideration is â€Å"if the increasing number of immigrants has influenced the number of employment opportunities for the native Canadians.† There are various factors that play their role in linking immigration and employment status in Canada. Canada is spread on a large piece of land, naturally enriched with natural resources. On the contrary, the low fertility rate of Canadian natives is not compatible with the number of workers required for the establishment and development of industries needed to make use of Canada’s natural resources for the well-being of the country. It is this characteristic feature of the Canadian culture that necessitates the influx of immigrants to overcome the deficiency of skilled workers in order to ensure economic growth and development of the country. This, undoubtedly ma y cause an apparent job-deficit for the native Canadians, yet the practice is likely to bear fruitful results in the long run as a result of a development in the industries followed by increased GDPs in the years to come. Also, the benefits of immigration outweigh the harms it may cause to the native Canadians in that the development in business results in increased facilities in no time and a better life-style for the Canadians to enjoy. Besides, Canadian policies tend to eliminate fears of economic drawback on the part of the native Canadians by creating a difference between the wages of a native and an immigrant working parallel to each other in terms of skill and position. Canadian policies tend to adopt a biased approach when setting wages in favor of the natives, who get higher

Australian Economy Essay Example | Topics and Well Written Essays - 2000 words - 2

Australian Economy - Essay Example The unstable nature of growth however affected the general economic climate in a way. For instance, because the economic wave stability was generally unpredictable, investors could hardly predict what the future held for them in investing in Australia. Specific Governmental and Reserve Bank Economic Policies that were introduced in the last 2 years - Budget The budget has the tendency of deciding the future economic hopes of a country because it serves as the blueprint economic policy implementer. For this reason, the government of Australia took certain important steps by way of their budget that were directed towards ensuring economic growth. One of such policies through the budget was the fact that the government through the budget encouraged the establishment and opening of new small and medium scale businesses by the introduction of Small Business and General Business Tax Break, which was â€Å"expanded to allow a bonus deduction of 50 per cent to small businesses with a turnov er of less than $2 million that acquire an eligible asset between 13 December 2008 and 31 December 2009 and install it ready for use by 31 December 2010† (Australian Regulatory Compliance Review, 2010). Again, the budget was highly focused on human resource and labor in general as the pension age was slightly increased to 67 years. This was aimed at retaining and cheering experience in the labor front and ensuring that the human resource base to man Australia’s economic drive was not depleted. Finally, the government saw a lot of hope in the future of the economy of Australia, planted in the need for the country to be self sufficient as far as production is concerned. For this reason, â€Å"The Federal Government used the Budget to launch a new paper on innovation that powered ideas paper canvasses proposed improvements and incremental changes to the existing National Innovation System† (Australian Parliamentary Library, 2010). - Interest Rates The last two years were years that the world as a global entity was resurrecting from previous years of economic shock, meltdown, crisis or however it may e described to depict an undeserving situation. For this reason, it was very important that the policies by the reserve bank and government would be centered on the people and empowering them to be investment oriented. For this reason, the periods of 2009 and 2010 was one season that the reserve bank maintained most of its lending and interest rates. The reserve bank with consultation with the government also ensured that the interest rate was generally low and affordable for borrowers. In some cases, there were even downward cuts on the interest rates and reasons for these decisions included the need to boost the demand for credit to undertake investment projects as demand for credit rose just 0.6% (Rate Detective, 2011). Again, there was the need to conform to global trend such as China cutting its official interest rate by 1.08% (Rate Detective, 2011). Such a move was necessary to ensure that investors did not opt for countries with lower interest rates but for Australia. - Export Promotion Policy In times of economic recovery, exports have been identified to be more profitable to countries than imports (Koduah, 2008). This is because exports attract a lot of revenue in the form of taxation. Knowing this, the Australian government over the last two years was not blind on putting measures

Investigation and evaluation of the opportunities of food retailer Essay

Investigation and evaluation of the opportunities of food retailer Tesco expending into Mumbai of India - Essay Example According to Czinkota and Ronkainen (2007) international marketing can be portrayed as a process of planning and carrying out transaction across the national boundaries, in order to create an exchange and to satisfy the needs of the organization. The forms of international marketing are generally export-import trade, wholly owned subsidiaries, joint ventures, licensing, management contracts and turnkey operations. This study aims to evaluate the opportunities of food retailer Tesco expending into Mumbai, India. In other words, the objective of the study is to uncover the opportunity for food retailer Tesco to setup its business in Mumbai. Tesco PLC, the UK based multinational general merchandise and grocery retailer is presently headquartered at Cheshunt, Hertfordshire, England (Yahoo Finance, 2012). It was founded by Jack Cohen in the year 1919. Based on its strong performance and determination, the company has been able to achieve colossal success in a short span of time. The compa ny is considered as one of the largest retailers of the world. Tesco is the second largest retailer in terms of net profit, just after Walmart, and the third largest retailer in terms of revenue, just after Carrefour and Walmart. ... Earlier the company used to position itself as a company which sells in large quantity and at low price. However the company has repositioned itself as a company that appeals to a mass customer through its wide range of products and value. The strategy paid off to a large extent as Tesco was successful in setting up 2000 stores more from the period of 1990 to 2005. Figure 1- Countries Where Tesco Operates (Source: DeadAnarchistPhil, 2012) With depressing economic environment, people are moving towards cheaper and value products. Some of the established players of Mumbai grocery retail industry such as Reliance Fresh, Aditya Birla’s MORE, Big Bazar, Metro Cash & Carry, and Marks & Spencer among others. (Source: Sood and Jashnani, 2012) Considering the present market conditions, the only way a company can earn profit is by satisfying the customers. Therefore proper segmenting and targeting the customers have become an indispensible task. In order to segment a market, companies n eed to consider factors such as psychographic aspect, demographic aspect, geographic aspect and behavioural aspect (Lao, 1998, p.114). According to the reports, the current strategy of the company is developed to compliment the vision, address the changing needs of the consumers and to satisfy the global nature of the company’s business. The strategy of the company is to create highly valued brands and customers with a variety of choice. This strategy helps the company to target customers from different segments of the society (Tescoplc, 2012). In addition, it also allows the company to realise economies of scale in the field of marketing and production. Moreover Tesco has the ability to sell products at a low price and therefore the company should deem catering to

When will they run out Essay Example | Topics and Well Written Essays - 500 words

When will they run out - Essay Example Scientists predict that no sooner than later people will start getting badly affected by floods, extreme temperatures, climate changes and lack of water and food. Human population will increase by 50% by 2050 and we know that human activities greatly affect the climate changes thus causing global warming. For example, human induced developmental activities in factories and industries lead to emission of toxic and greenhouse gases thus increasing the earth’s average temperature (see Figure 2). Ehrlich and Ehrlich state that â€Å"Global warming, acid rain, depletion of the ozone layer, vulnerability to epidemics, and exhaustion of soils and ground-water are all†¦related to population size.† This leads to planet un-sustainability because crop failures and AIDS will lead to many premature deaths in the coming years which will be a natural measure of population control. Since our planet’s natural resources are already being over-consumed, the increasing populati on will naturally cause global warming because too many people consume carbon-based energy. We use energy to exist, develop and grow. Energy makes our lives simpler for us. The energy industry produces for us heat, light and force. Since our needs are not going to get fewer in the next twenty years, therefore, as Taylor and Parish (viii) state, â€Å"By all accounts, the energy sector will be the growth industry of the future.† They also state that â€Å"The U.S. Department of Energy estimates that the United States will need 44 percent more electricity by 2020.† This is because the demand will increase since the country’s economy and every other field is digitally driven. Today, computers and all other technological tools take around 13% of electricity produced and this is going to increase in the coming years. Also, since internet has become a significant source of telecommunication in all informational and entertainment activities, the demand of energy will continue to increase. Renewable energy

Motivational Theories and Factors Essay Example for Free

Motivational Theories and Factors Essay Stress and conflict in the workplace can cause major emotional and physical damage to the facility and workers. In the past, there have been reports of tragedies caused by disgruntled workers who may have clocked in with a gun in hand. We are going to look into ‘three motivational theories including the relationship of stress and conflict in relation to individual motivations. ’ Many factors can motivate employees while at work. Some of the motivating factors could include the structure of the lives of the employees before they became employed. Personality is a big factor in employee performance and motivation. Someone that is an introvert may not have the same mind set as an extrovert. This will definitely dictate how that employee behaves and responds to directives at work. Turmoil has happened in recent years in workplace settings. Let us take a closer look at a tragic workplace incident. Omar Thornton was a thirty-four year old black delivery driver in Manchester Connecticut. On August 4, 2010, he signed his resignation papers in front of witnesses after he saw video footage of him stealing beer from his company. Before leaving the room he reportedly pulled a gun and started randomly shooting workers he came across. In the end, he killed eight, leaving two wounded before he killed himself. Thornton’s relatives and girlfriend said he had been harassed in a racial manner. This story is not the only one we have seen in the news. It proves that motivation can be a source of good behavior or negative. In Thornton’s case he was motivated by what he thought to be racially aimed mistreatment from his white co workers. This caused him to become stressed and it reached a deadly point of conflict, a him against them scenario. In the real world, no employee should allow their job stress to motivate them to take lives or destroy property. Stress can lead to serious consequences, whether it becomes a health issue or affects performance in a negative way. If employees are in constant conflict over management issues, pay working conditions or other concerns, this can lead to low moral among the employee congregation. It won’t matter if all employees are involved in the struggle, dissatisfaction can spread like sand into each individual’s boundaries. It will be the main topic around the water cooler each day. The job for management is to keep employees motivated in the right direction for the good of the company and its productivity. Management can help decrease the incidents of job dissatisfaction by following these steps. Positive reinforcement should always follow an employees job well done. When problems or disagreements arise the discipline should fit the crime. All persons who live up to their expected performance should be treated in a fair respectful manner. Goals should always be well pronounced so that no employee will say they didn’t know what was expected of them. Some jobs may need to be restructured to generate better productivity. All employees who perform in an acceptable capacity should be rewarded fro their compliance. Increased pay or a truck load of benefits may not always be at the top of the list when it comes to employee motivation. People want to feel needed and appreciated on the job. They want to know that their work is worth something. So, to decrease the incidents of stress, unfairness which can lead to conflict and disgruntled or dissatisfied employees, companies need to place value on employees who are doing what they are asked. When conflicts arise, there should be a procedure in place to allow every voice to be heard. When I am involved in stressful work situations, I bring it to the attention of my department manager. I do not attack an individual, I attack the cause of the problem. I follow the company’s guidelines for resolution, it has always worked for me. Since I started this class, I have learned that positive external motivation can also decrease or prevent stress in the workplace. So there should be a plan already in place to head off negative incidents.

REMEDIAL WRITING PROGRAMME FOR ELEMENTARY STUDENTS

REMEDIAL WRITING PROGRAMME FOR ELEMENTARY STUDENTS The purpose of this study programme is to determine if students from the elementary level of Hin Hua High School (Chinese Independent School) improved in their ability to write in English after having studied specifically developed curriculum. The 7-hour remedial programme is to be conducted once the academic department releases the final assessment grades. Fifteen students with the lowest score were selected using the criterion method to undergo the remedial programme. the importance of all six major aspects of writing measured in the English Test which comprises mainly punctuation, grammar and usage, sentence structure, strategy, organization, and style. It is believed by attending the remedial programme selected students would be able to show the ability to make and articulate judgments by taking position on an issue or problem. Besides sustaining a position by focusing on the topic throughout the writing. They are alson expected to develop a position by presenting support or evidence using specific details and make inferences based on support or evidence. Most importantly, they should be able to organize and present ideas in a logical way by logically grouping and sequencing ideas. Hence communicate clearly by using language effectively and by observing the conventions of standard written English INTRODUCTION As a language teacher, I often select writing tasks from language textbooks to help students improve their writing ability. Behaviorists, communicative, cognitive, and discourse theories could influence writing approaches in language textbooks. Each theoretical framework has provided us with a better understanding of the multiple dimensions and purposes of teaching writing. A review of the developments in writing pedagogy leads us to conclude that we could teach writing as a means to improve linguistic, rhetorical and communicative competence or as a discovery and cognitive process. The writing tasks that we select from language textbooks and assign to students could reflect one or some of these pedagogical purposes. As teachers, we need to question and understand the pedagogical assumptions of textbook writing tasks so that we can select tasks that will help our students become confident writers and independent thinkers. Primary students entering the secondary school level (high School) are challenged not only to learn new content in the disciplines but also to communicate this. A significant number of students will not have adequate academic literacy levels to be able to do this successfully (Jones and Bonanno, 1995 (1). Atlhough traditionally students were expected to develop academic literacy skills without any explicit teaching of these skills, schools now recognize the increasingly diverse backgrounds of their student populations and have put in place mechanisms for helping students develop their academic literacy. These have included the establishment of literacy and learning units as well as the requirement for school curricula to address the teaching of writing skills including communication skills. English Learning Centre of Hin Hua High School Klang, like other literacy and learning units, has been involved in a number of collaborative projects with teachers involved in teaching Junior One to integrate the teaching of communication skills into the curriculum (Webb et al, 1995, Taylor and Drury, 1996). These initiatives have resulted in the development of new teaching materials and approaches as well as new practices of assessment and feedback. However, as subject area curricula are being adapted to computer-based forms of learning, it is also necessary to consider how the teaching of communication skills can be integrated into these programs or how the teaching of communication skills can be contextualized within the learning of subject area knowledge. With the current demand for propheciuency in English Language great importance has been given to developing programs to instill good writing modes to the elementary learners which aims to help students become successful editors of their own writing. 1.1 LITERATURE REVIEW Writing skills have been identified as to improve students thinking. Moffett and a few others have developed cognitively sequenced curricula for elementary and secondary writing, college composition, when it is sequenced at all, tends to rely on structural or rhetorical arrangements, which are neither sequential nor cumulative. Progressions from word to sentence to paragraph to theme confuse quantitative with qualitative growth, while rhetorical sequences confront students with cognitive problems of different but equal complexity. In short, from a cognitive perspective, most writing instruction in higher education is consistent with that in secondary education: what Stephen Judy described as Advanced Hodgepodge in high school gives way to Arrogant Hodgepodge in college. A large and growing body of research, however, shows that cognitive development follows a hierarchical sequence of stages and suggests that a curriculum can be sequentially organized to promote cognitive development. Blooms Taxonomy of Educational Objectives provides some essential connections between the cognitive abilities we expect of college students and a curriculum that can stimulate those abilities Blooms Taxonomy is one solution to the cognitive hodgepodge of the writing curriculum. It allows us to sequence instruction and assignments in ways that speak directly to students developmental needs. From least to most complex, For writing instruction the taxonomy provides a flexible model of what happens cognitively in the learning process Bloom described a six stage sequence: Knowledge, Comprehension, Application, Analysis, Synthesis, and Evaluation. (See Figure 1) Figure 1.0 The flow chart of Blooms Taxonomy At each new level, thought processes build on and encompass previous levels. Implicit in this structure is the assumption of an ascending scale of difficulty and comprehensiveness. Thinking at the comprehension level is more demanding than at the knowledge level; cognitive problems requiring synthesis or evaluation encompass all the preceding levels. A review of Blooms definitions for each taxonomic level suggests what such a cognitively-based writing course might entail. Although the focus of each level is cognitive, rhetorical issues of audience and purpose are equally appropriate and can be specified for any assignment. Most of all, the taxonomy allows us to contemplate the value and feasibility of a cognition-based curriculum in writing. Such a curriculum would reflect the hierarchical relations of the various thought processes and would help to control for cognitive complexity in writing and thinking about distorting natural discourse. In this form, writing or writing-intensive courses would systematically develop students thinking skills rather than leaving them to chance or, worse, blunting the writers still-developing ability to explore and express ideas. In short, a cognition-based curriculum ensures that students participate fully in using writing as a mode of learning. 2.0 INTENDED PURPOSE The remedial programme is targeted for the elementary learners who are in the process of upgrading their writing skills to the pre -intermediate level. A total of 15 students are selected from the age group of 13 years old based on the final semester examination results. The examination basically structured in accordance to the textbook currently used in the school curriculum ,New Opportunities (Pearson Longman-Cambridge). Basically the (Stiggins to highlight achievement differences between and among students to produce a , 1994). School systems might want to classify students in this way so that they can be enhance their competency level even further. The major reason for using a norm-referenced test (NRT) is to classify students. NRTs are designed on dependable rank order of students across a continuum of achievement from high achievers to low achievers be properly placed in remedial or gifted programs. These types of tests are also used to help teachers select students for differe nt ability level reading or mathematics instructional groups. As the selected students fall under the below average group in Paper 1(Writing Assessment) whereby there are two parts that the had to complete here: SECTION A Notes Expansion and SECTION B Continuous Writing (Choose one topic out of five given) From the academic analysis it was found that majority students failed in Section B where it consists of 25% of the total marks of 40% of the Writing paper. Thus they are required to attend a 7 hour remedial programme to improve their writing skills by at least 85%. 3.0 PURPOSE OF REMEDIAL WRITING PROGRAMME The reasons for the remedial program to be initiated is to better the learners in their writing skills and strengthen it so that they have all capabilities to be promoted to the next level but due to certain minute factors they fail to adhere to the standards of the pre-intermediate level. Thus these students are carefully selected using the criterion method to undergo the 7 hour remedial programme. In order to drill and motivate these students in the remedial programme an enriching lesson plan is formulated to create a positive outcome at the end of the the 7 hour remedial programme. The purposes for emphasizing writing skills are to produce who can comprehend teaching and learning in a positive mental attributes. There is a wide body of research suggesting that assessing students written performance is a valuable undertaking. Not only is an instructor able to help a students progress, but also the instructor can facilitate the learning process and the learning outcomes by being aware of student performance throughout the academic session. Figure 2.0: The Purpose for Teaching Writing Undeniably, 3R skills are important and necessary in daily living. They are also needed to support the development of a knowledge-based economy. Recognizing these needs, the school has initiated and implemented programmes to identify students who have not mastered the 3Rs. These programmes are designed to specifically address and overcome the inability of students to master the 3Rs. This is in line with the essentialism which instills students with academic knowledge and character development. Among the programmes that have been implemented in schools are the Early Inter ­vention Reading and Writing Class, Basic Skills for Reading, Writing and Counting Programme and the Literacy and Numeracy Programme at Level One. 3.1 Sub-skills of Writing Besides drilling and enriching the remedial learners with the core writing skills , there are also exposed to the importance of sub-skills in their learning such as: I Manipulating the script of the language: handwriting, spelling and punctuation. II Expressing grammatical [syntactic and morphological] relationships at the sentence level III Expressing information or knowledge in writing: explicitly implicitly IV Enrichment of Vocabulary PART B 4.0 Objectives of the 7-hour remedial programme The main aim in introducing and implementing the remedial programme particularly in the aspect of writing skills is to mainly: to develop competencies in writing skills among learners to move from a teacher-centered didactic model to a student-centered constructivist model to acquire the ability to write in a more clear, concise and acceptable manner 5.0 Instructional Design : Using the ADDIE Model to Build Writing Competency Among Remedial Learners Table 2.0 ADDIEs Model 5.1 Framework The generic term for the five-phase instructional design model consisting of Analysis,Design,Development, Implementation, and Evaluation. Each step has an outcome that feeds into the next step in the sequence. There are probably over 100+ different variations of the generic ADDIE model. Instructional design aim for a learner -centered rather than a traditional teacher-centered approach to instruction, so that effective learning can take place. This means that every component of the instruction is governed by the learning outcomes, which have been determined after a thorough analysis of the learners needs. This phases sometimes overlap and can be interrelated; however they provide a dynamic, flexible guideline for developing effective and efficient instruction. Figure 3.0 Instructional Design: Using the ADDIE Model 5.2 ADDIES Theory The ADDIE instruction model for this desin is outlined by Smith and Ragan(1995) in their book entitiled Instructional design. The focus is n 5 points Analysis, Design, Development, Implementation and Evaluation. From this theory the analysis has proved that there was a need to conduct remedial programme for the elementary low scorers where an opportunty was given to learn and develop basic essay writing skills. 6.0 Remedial Education Programme In Malaysia, the importance of remedial education gained attention in the 1960s. Results of a pilot project in nine schools between 1967 and 1970 showed a need for remedial education, especially for pupils in rural areas. This paved the way for remedial education programmes in primary schools. The pioneers in the field attended a two-year intensive course on remedial education in the United Kingdom. Subsequently, a national series of seminars and workshops on remedial teaching were organized. With the exception of small schools or under-enrolled schools, every school is allocated one remedial education teacher. At the school level, a Remedial Education Committee is formed, comprising the headmaster, remedial education teacher, class teacher, subject teacher, resource centre coordinator, and other teachers as members. The introduction of a new curriculum for primary schools in 1983 implied a return to the basics in education. The ultimate goal was to ensure that no pupil is illiterate by the year 2000. The implementation of the remedial education programme for children in Primary 1-3 is to ensure that they master the 3Rs. Children who have been recommended for remedial education are required to attend remedial classes. As of 1999, 54,000 primary school children have undergone the intervention programme. In addition to improving and enhancing teacher development, the Malaysian government also works towards improving the curriculum at school to meet the changing needs of the economy. During the Fourth Malaysia Plan, the primary school curriculum was revised with the aim of providing and establishing a firm education in reading, writing, and arithmetic. This led to the development of a new curriculum emphasizing the 3Rs. Studies looking at the returns to education in Malaysia have found positive results in those who have had some form of formal education, thereby providing support to the government guidelines on the primary curriculum which emphasizes the acquisition of basic skills.Education in Malaysia , changing very rapidly responding to the emerging focus of lifelong learning; the growing emphasis on learning; as opposed to reaching and the development of the new delivery systems 6.1 The Educational, Philosophical and Psychological foundation Elementary education shall aim to develop the spiritual, moral, mental and physical capabilities of the child, provide him with experiences in the democratic way of life, and inculcate ideas and attitude necessary for enlightened, patriotic, upright and useful citizenship. To achieve these objectives, elementary education curriculum shall provide for the: inculcation of spiritual and civic values and the development of a good citizen based on an abiding faith in God and genuine love of country; training of the young citizen in his rights, duties and responsibilities in a democratic society for active participation, in a progressive and productive home and community life; development of basic understanding about Malaysian culture, the desirable tradition and virtues of our people as essential requisites in attaining national consciousness and solidarity; teaching of basic health knowledge and the formation of desirable health habits and practices; development of functional literacy in English as basic tools for further learning; and acquisition of fundamental knowledge, attitudes, habits, and skills in science, civics, culture, history, geography, mathematics, arts, and home economics and livelihood education and their intelligent application in appropriate life situations. The Elementary Basic Education Curriculum focuses on the tool learning areas for an adequate development of competencies for learning how to learn. The goal of Instructional design is to support the cognitive processes that result in learning (McGriff). The expected outcome of instructional design is to provide knowledge and skills to people. The three major learning theories are Constructivism, Behaviorism, and Cognitive. Instructional Design is based on constructivist principles. Instructional design is associated with instructional systems development (Leshin et al, 1992). An Instructional System is the arrangement of resources and procedures to promote learning (Berger and Kam). 6.2 Programme Design: ADDIE Model ADDIE is a general-purpose model, which can be used to create instructional products and program design. ADDIE is the acronym for Analyze, Design, Develop, Implement and Evaluate and summarizes the five steps in the Instructional Design process. The instructional designer makes decisions critical to ensuring the effectiveness of the educational experience in each phase of the process. In accordance with the process improvement model, the five phases are a loop, with the improvement of learning outcomes as the goal. Dick and Carey and Kemp (Kemp, et .al, 1998) expanded the ADDIE Model into nine elements. The Dick and Carey Model uses a Reductionist approach in breaking instruction down into smaller segments targeting sub skills. The learner is required to master of sub skills, which are aggregated to achieve overall skill mastery and learned behavior. It provides a systematic approach to curriculum and program design. Teaching is essentially a philosophical endeavor and therefore educational activity can be conceived within the context of a philosophy or worldview. The curricukum refelects the art and craft of teaching. Educational technology can provide diversity of thinking regarding curriculum and instruction which would be curriculum theorizing. 6.2.1 Analysis Basically the nature of the students whom the remedial programme to be conducted are students who learn English Language as a second language. They are originally from Chinese speaking families with a minimum exposure to English Language. Due to the expectation of the school and the educational needs in adhering English as one of the core subjects in school these students are required to have in depth knowledge and skill in it. All of them have been educated in the Chinese primary school education system. Based on the final semester examination results 15 students are selected to undergo remedial programme as they fall in the border line cases .The students acquire poor writing skills, while being able to construct sentences fairly well, they seem to have great difficulty in organizing and developing their ideas into the form of an essay that has an introduction, body and conclusion. In order to promote these students to the next level that is the pre-intermediate phase from their origin elementary level the English Language Department found it vital for them to attend a 7-hour remedial programme in order to find solution to this situation. All of them need to further develop their writing skills in term of cohesion and coherence; time and practice. 6.2.2 Design The main design goal for our programme would be on the cognitive strategies of being able to develop an idea for writing since all of them com e from a very similar background and have basic sentence writing skills. Besides the development of language in the mechanics of sentence construction such as syntax, grammar, structure, etc given priority. R.Gagne(1965) divided learning into 5 categories: Verbal or declarative knowledge, intellectual skills, cognitive strategies, attitudes and psychomotor skills. The learning goals are also in connection to these categories to try to put educational value behind our goals. At the same time the goal also reflects competences outlines by Benjamin Bloom (Bloom,1956). These include: Knowledge, Conprehension , Application, Analysis, Synthesis an Evaluation. These give our goals validity whereby competencies are incorporated in bringing about concrete task for learners that we assign in order to achieve their goals. Hence in the evaluation phase, we can use this aspect to find out the validity and the accomplishment of the learners in implementing the programme. Learning Goals and Type of Learning OBJECTIVE STANDARD GAGNES DOMAIN BLOOMS TAXANOMY Learners will identify an essay topic and 3 sub-topics Criteria established by Hin Hua High School, English Language Department Cognitive strategies Synthesis Learners will be able to write a 3 paragraph essay with an introduction, 2 sub topics to include their opinions, ideas and conclusion Criteria established by Hin Hua High School, English Language Department Declaration Knowledge Intellectual Skills Synthesis Evaluation Application Learners will be able to use the library and Handouts to research printed information on their topics Criteria established by Hin Hua High School, English Language Department Procedural knowledge (declaration knowledge) Knowledge Learners will be able to use proper mechanics of grammar syntax Criteria established by Hin Hua High School, English Language Department Intellectual Skills Application Learners will be able to present their topics in class Criteria established by Hin Hua High School, English Language Department Declaration knowledge Comprehension Table 3.0 Learning Goals and Type of Learning 6.2.3 Development In order to establish a approachable remedial programme for the elementary learners , we English teachers have developed a remedial programme which will undertake a 7 hour learning process. The teachers from the same level have brainstormed and come up with a course content for the 7-hour teaching and learning programme. The teachers from the same teaching level are the best person to create the lesson as they deal with the same competency level of students all the time and are considered experts in their area. Besides this, they will be able to make he printed and computer materials and added step of getting the right content for the level. On top of that since they have already been teaching in the same scope so they will be undoubtedly familiar in the process of teaching and guiding the learners in order to make the remedial programme a success. 6.2.3.(1) Procedure The remedial programme would be in the English medium since the main objective is to improve writing skills among elementary learners. The programme consists of 6 regular sessions and followed by a review and a test day. Each hour is scheduled to be conducted for 60 minutes ***Details on the whole programme given on Part D 6.2.4 Implementation Further to the development to the development the teachers would be equipped with intact course content for he programme. The module would be prepared in balance with the time frame allotted for the programme. Any teacher who is selected for this task should be ready to undertake the teaching process based on the scheme that has been prepared. Al l 15 students will be instructed to attend the programme for 7 hours. These are the various aspect of implementation emphasized in the learning process: Table 4.0 Learning Process Implementation 6.2.5 Evaluation The evaluation phase consists of two parts: formative and summative. Formative evaluation is present in each stage of the ADDIE process. Summative evaluation consists of tests designed for domain specific criterion-related referenced items and providing opportunities for feedback from the users. Primarily the evaluation is done in two parts. The first phase will be the evaluation of student work based on the objectives in the Learning goals and type of learning listed above. Students will be rated by their teacher based on the A,B,C,F criteria set by the English Department. An A is excellent work, B is average, and C will mean student needs improvement. An F would mean that student failed the writing assessment with below 60% of mark. Students will be evaluated at each stage of the course. The department will use this evaluation in order to find out how they might need to modify the programme in the future. A summative evaluation will be conducted as outlined by Smith and Ragan(1999,p.352). Those authors explain that in order to evaluate the effectiveness, appeal, and efficiency of instruction, a collection, analysis and summary of data on students ia essential. In our designed programme an exam is built to access students of their mastery on the abilities taught during the programme.Students are to show their capabilities in their understanding and knowledge taught to them by completing the set of homework targeted to them. Students will be graded on from 1 to 5 for their abilities in each of the following sections: Student name Student able to choose a topic n sub-topics Student able to use handouts information Student able to complete the essay Score dated from 1 to 5 1 : poor 2 : Able to understand the writing concept with some guidance 3 : Able to complete the task with help and support 4 : Able to understand the concept and complete the task individually A pre-test and post-test can measure how well learners achieved the learning objectives. However, it usually takes more time and effort to measure things such as whether the learners will use their training. This evaluation phase can extend for months. Upon completion of the programme the students feedback will be collected to further gauge the success of the programme. Questions are also answered on a scale of 1 to 5. 1 is low and 5 is high. The standard questions constructed are as below: Were you satisfied with the content of this course? Were you able to understand the teachers explanation? Were you able to put into practice elements that you learnt? Did you fond the course interesting? On a scale of 1 to 5, what is your general feeling about the course? PART C 7.0 REVIEWERS COMMENTS Below is the summary of the feedback received from two of the Senior Teachers from the English Language Department of Hin Hua High School regarding the 7hour remedial programme on writing skills. Reviewer 1: Mdm Annaletchumy Reviewer 2: Ms Sastina The strengths and weaknesses of the newly developed Remedial Programme for Elementary Students Strengths 1. Learning by actively participating in group discussion 2. Encouraging students to construct their own ideas and knowledge of the topic 3. Student-centered rather than teacher or subject-centered 4. Teaching aid contributed to students visualization on the topic given 5. Suitable to students development level 6. Group work enables students to self express, to be self-confident and self- awareness 7. Encourage teacher to develop students creative thinking abilities 8. Emphasizing the concept of group work and peer evaluation where no student Is left behind 9. Encouraging the co-operation among students and teacher positively 10. Enables student to have a positive mindset in creative writing Weaknesses 1. Unsuitability of activities for crowded room 2. Lack of materials used as aid for pre-writing task 3. Lack of teachers evaluation on the first phase of writing 4. Certain task may take more time than the planned time 5. Peer evaluation on writing inappropriate approach for elementary learners 8.0 Summary of Review Summarized below are some of the accomplishments and challenges I personally went through in construction the remedial programme: 8.1 Strengths 8.1.1 Improved students attitude and motivation Students are mentally prepared to participate in the programme because students agree to a particular pace, workload, and learning environment from the beginning. 8.1.2 Creating Learning Communities: Classes function as teach communities both teacher and their students benefit in both social and academic areas from working with each other over a entire programme. 8.1.3 Eliminating Stigma of Dependency: The concept group work and peer evaluation removed the stigma of being too dependent on the teacher Writing materials. 8.2 Weaknesses 8.2.1 Students participation Some learners will not contribute in due to the lack of interest or proficiency 8.2.2 Stipulated Time The period allotted might not be sufficient for certain task. Thus this will delay or sometimes interrupt the whole programme structure. 8.2.3 Genuinely in peer marking Some learners will not adhere by the rules set in peer marking when it comes to assessment. Favoritisms and self -centered will influence the observation 9.0 Conclusion It is expected that by attending this model of English remedial instruction it will be beneficial to low English achievers. Students will gain substantially in grammar and vocabulary and they will also gradually improve in their overall English competence. Based on the comments from the reviewers it can be concluded that learners will be effectively improve their English writing skills through the prepared course module for the remedial programme. A well-designed course will definitely give them encouragement and support to elevate their English proficiency and be prepared for the next level , pre=intermediate. 10.0 PART D 7 HOUR LESSON PLAN REMEDIAL PROGRAMME ENGLISH LANGUAGE LEVEL: ELEMENTARY LENGTH:420m LESSON TYPE: WRITING SKILLS Aim: by the end of my lesson, students will be able to write a full-length essay on Endangered Species and improve their approach of writing strategies. Subsidiary aim: students will be able to improve their use of linking words in controlled and less controlled writing activities on Endangered Species Evidence: (How will I know I have achieved the aim?) Students will be able to complete gist and short writing strat